Apple notes that House does not seem much different, and he notes that at least he has not given up. As she signs, Apple talks about how she was an architect but gave it up after her corneal transplant. He then asks Apple to sign a consent form to receive chemotherapy. He goes to her room and signals an emergency when he cannot find the medical records on Apple's bed. The team has nothing new and House orders chemo for the cancer he suspects she has. There are no leaks but Foreman spots what appears to be a core lesion.ДЄpple's heart starts racing but there's no indication her colon is leaking. House still believes in cancer and Kutner suggests they use a high-pressure water jet to apply pressure to Frank's colon. House returns to the hospital where Kutner and Foreman inform him the colonoscopy proved clean. House asks if there is something, and Lucas admits there is not. House meets with Lucas, who figures that House wants to hire him to check out Wilson. Kutner suggests a perforated intestine and bacterial infection that spread through the blood and infected all the organs. They determine Frank's brain is clean and House still suspects cancer. Frank suddenly stops breathing and dies despite Taub's efforts. Taub reluctantly tells Frank's wife the truth. They need to do a brain biopsy and appeal to Frank's wife for approval. They conclude he's a private investigator and House admits hiring him. The coffee machine repairman interrupts to berate Taub and Thirteen for being idiots. House reviews a video of the kickboxer looking for signs of brain damage. However it's soon revealed that this is nothing more than Apple's imagination and back in reality, House realizes that Apple is hallucinating. As he swings the meat cleaver towards her, Apple starts screaming. He then states that it is too late to remove her eye, and instead has to remove her head, as he brandishes a giant meat cleaver.

House then states that her eye thinks it is fine, but that eyes do not think, but only brains. She had taken an eye test and had gotten it wildly wrong, but did not squint. Foreman arrives to inform House that Apple's eye is failing and they have to remove it. Finally House goes with a diagnosis of cancer and orders them to run more tests. The team is unable to determine a common denominator and House is more concerned about Wilson's absence. Thirteen interrupts a college class to confirm the math instructor, Apple, had a corneal transplant five years ago, then informs her that four other people who received a transplant from the same donor died.ДЄpple is taken to the hospital where they determine four of the victims are dead and one more, an elderly man named Frank, is on the verge of death. A tuba instructor starts coughing up blood in the middle of a lesson and expires. A fighter dies in the middle of a MMA match. On a construction site, a crane worker dies in his seat. Two women are playing tennis when one of them collapses, clutching at her chest. ' Not Cancer' is the second episode of the fifth season of House and the eighty-eighth episode overall. 2nd episode of the fifth season of House ' Not Cancer'

House md season 5 episode 2